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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

高部长称,目前全国商品交易市场已经超过8万家,社会消费品零售总额在年底预计达到30万亿元,而消费对GDP的贡献接近60%。
speculative

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

《人物》评选的电影史上35位美人(1)
线索可能隐藏在价格之中:H股很便宜。H股指数市盈率为7倍,低于西班牙(该国失业率达到22%)、巴西(该国依赖大宗商品,因而也依赖中国)以及受中东乱局影响的土耳其和埃及。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

JINX: THE LIFE AND DEATHS OF ROBERT DURST (HBO, Feb. 8) Andrew Jarecki (“Capturing the Friedmans”) directed this six-part documentary series with the cooperation of Mr. Durst, the New York real estate scion linked to several killings and the unsolved disappearance of his first wife.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

2015年风头最劲的品牌:在新款切诺基的拉动下,Jeep在2014年的销量惊人地拉高了44%,而斯巴鲁的销量则静悄悄地提高了21%,现已成为美国第十大最受欢迎的汽车品牌。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

当你走进来的时候,我对你的认识比你的想象中的多。我在网上寻找关于你的资料,利用我自己的关系网来做面试前的背景调查。
The contiguous United States set a temperature record in 2012, a year of scorching heat waves and drought. But, mostly because of the unusual chill in the East, 2014 was only the 34th warmest year on record for the lower 48 states.
反对:在颁奖季前一年早早上映可能不利于其冲奖。
In the heart of Wan Chai, on one of Hong Kong’s busiest streets, stands a 33-storey office tower that earlier this year became the second most expensive property to change hands in a city that boasts the world’s costliest property market.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

这与上月制造业采购经理人指数(PMI)的表现相一致,PMI显示制造业活动有所扩张。
6. Data scientist
[kri'eitiv]
与此同时,中国首富王健林等人士对中国国有企业在欧洲投资的事情表示担忧,声称它们缺乏国际管理标准。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

On China's Twitter-like Weibo, many netizens thumbed up the boy's bravery and calmness in the face of such emergency.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The impact will also ripple out to some net commodity importers, Mr Williams believes, with higher commodity prices likely to boost the price of resource-intensive manufactured goods such as steel, bolstering the value of exports from the like of South Korea.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Horowitz, speaking to radio station RTE, said he was keen to keep the new Bond true to the 1950s creation.
Do your homework. Read the assigned pages, and then some. Plug your topic into the Internet, grab another book at the library, and see what else you can learn about the subject.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

31岁的罗西每天的工作就是计算五角大楼在养老、医疗和教育福利方面未来的成本。但他说,这份工作不仅仅是鼓捣电子表格数据。他还要与其它政府部门进行沟通,并就金融模型与同事举行头脑风暴会议。
6. 米兰达·兰伯特(Miranda Lambert),《白金》(Platinum),RCA Nashville。兰伯特很快从坚强的新贵蜕变为光芒四射的乡村乐贵族,这张《白金》是她最好的专辑,她带着轻松的权威之感逾越了界限。专辑中伤感与世俗的情绪交替出现,修饰和粗粝的比例恰到好处,这张专辑让人们明白她有着强大的力量,向任何低估她实力的人发出挑战。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

It plans to help at least 130,000 rural people cast off poverty and relocate 163,000 residents in 2017.
Will Tesla produce more than 250,000 Model 3s

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 未来的智能家居到底能有多智能
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Company: Nation Waste, Inc.
New construction will provide luxury options for renters with deep pockets, mostly in the boroughs outside Manhattan. In Brooklyn, 6,527 new rental units are expected to hit the rental market next year, nearly twice the 3,802 units anticipated for Manhattan, according to Citi Habitats.
来自民主党的奥巴马和共和党的罗姆尼在竞选活动中,都把重点放在如何修复萎靡不振的美国经济上。据估计,至少有1.2亿的美国选民将选举投票。
GM Masai Ujiri struck twice to position Toronto for a second trip to the East finals, nabbing Ibaka from the Magic and Tucker from the Suns.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 湖北省住建经济运行分析每月一次
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

随着经济增长放缓,中国政策制定者对银行放贷速度越来越担心。中国银行业监管机构的数据显示,去年中国银行业资产规模增加了逾72万亿元人民币(合11万亿美元)。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 创新推动海南自贸区可持续发展
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

5. 范冰冰 1700万美元
slice

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 2017年防腐涂料总产量将达600万吨
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

4.《欲望都市》掀起纸杯蛋糕热

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Hailed as one of the greatest films of all time, Taxi Driver tells the story of a depressed ex-Marine who attempts to assassinate a senator after being rejected by a woman he admires. While the titular taxi driver, Travis Bickle, lives a chaotic life filled with drug dealers and prostitutes, his story was never meant to be an unrealistic fantasy. Rather, it meant to expose the very real warning signs of a would-be gunman.
上海复旦大学社会发展与公共政策学院院长彭希哲周二告诉环球时报,在产业结构升级的过程中,劳动密集型产业搬离都市圈,是导致这一人口变迁的最主要原因之一。
触摸屏主要生产商蓝思科技的周群飞以450亿元的资本净值位列榜单第3。
In contrast, the average unit price of emerging market exports has been falling in year-on-year terms pretty much since mid-2012, hitting a year-on-year decline of 16.4 per cent in February 2016.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

年度最佳合唱:埃里克·丘奇、杰森·阿尔丁、卢克布·莱恩《The Only Way I Know》
Estimates for the size of the industry vary but Goldman Sachs figures suggest that sector loans grew from Rmb6bn to Rmb83bn between 2012 and 2014.
威廉姆斯指出,据凯投宏观估计,全球经济增长率将从2016年的2.5%上升至今年的2.8%,“新兴世界的大宗商品净出口国的出口额(以美元计算)同比增长应会达到20%左右。”
据英国《卫报》报道,在去年的伦敦时装周期间,有250名反皮草抗议者,2月份的玛丽卡特兰佐秀场也受到了抗议者激烈的抵制。
《阳光小美女》的夫妻档幕后团队将1977年鲍比.里格斯和比利.简.金之间的性别大战拍成了电影。55岁的里格斯是职业网球运动员,他向年轻的王牌选手简.金(当时世界排名第二)发起挑战赛,结果落败。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

营造80年代的感觉
世界杯锦标赛即将到来。 我想告诉你永葆美丽的一些要诀。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

While the political system will be fixated on preserving stability as new leaders take the helm, reduced economic flexibility could thwart Beijing's intentions to do so.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

科技厌恶症。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

而相对来说,普遍推出的新限购政策,并未让其他许多最近几个月表现突出的城市受到影响,房价同比依然大幅上涨。
7. 克里斯汀?斯图尔特
时间:2009-09-16 编辑:vicki
巴蒂说道:“纵观亚洲高校前三百名榜单,我们可以看到,现如今,动态、多样化且颇具竞争力的高等教育园区正在亚洲地区逐渐形成,中国则是这个发展过程中极其重要的一部分。”

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

网队重建的欲望已经超越了给波士顿另一个高顺位签的不情愿。大坑已经挖好,想要从坑里爬出来,你能做的只有:一步一步地,挑出合适的新秀,交易球员,以及签约。
We will promote the liberalization and facilitation of international trade and investment.
Sectors: out of favour
推进农业结构调整。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

adj. 快的,迅速的
上榜的12所美国学院平均而言是性别比例最为平衡的,女性学员比例为48%。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

复仇史诗电影《荒野猎人》获评剧情类最佳影片。小李子和导演伊纳里图一同上台领奖。
He added that there was an unavoidable issue with the original plot, because Pussy Galore was cast as a lesbian who cannot help but be overcome with lust for Bond.
同样地,如果TPP剩下的11国在美国退出后,能在日本的带领下设法挽救该协议,可能为该地区带来一些平衡。
《水形物语》
这确实是的。不过费城队近年来如此努力地垫底的一个被忽略的好处是:他们是如此地烂,以至于这会让其他竞相垫底的球队产生挫败感,因为他们很难做到和76人一样烂。在76人面前,小牛队至少只能算是中等水平的烂。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

当小李子上台领取奖杯时,制片人哈维·韦恩斯坦兴奋地拍拍他的背,全场观众起立为他喝彩。
Any decision by China’s policymakers to begin selling down the country’s huge reserves would have a large impact on markets.
或许,你能让高中版的韦德停下脚步,但是,当韦德长到6尺4寸时,他变得无法阻挡。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Holly Hunter reportedly keeps her best actress award, which she won for her portrayal of Ada McGrath in the 1994 New Zealand film, The Piano, at the New York offices of Joel and Ethan Coen. It sits alongside the statue Frances McDormand won for her role as the heavily-pregnant local police chief with the insatiable appetite, Marge Gunderson, in the Coens’ 1996 film Fargo.
I'm amazed that Durant didn't get broken in half back in high school, weighing in at 6'9'', 185 lbs. Lucky for Durant, he doesn't make his money banging against big forwards. He relies on his nasty quick-shot jumper.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

“One guy hired a marching band to accompany his announcement.”
从几乎所有单项指标看,巴黎高等商学院都没有排在首位,但它整体表现强劲。该学院学生毕业3年后的年薪为9.3万美元,位居第五;性价比以及毕业生国际流动性位居第三。该学院还在目标实现率方面并列第一(93%)。
If we ask "What salary are you looking for?" say you're flexible, or say it depends on the responsibilities of the job. Try not to name a salary unless we really push you, because that gives us a leg up in the negotiating.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

7、 阿斯顿·马丁必须有。不止如此,还要在异国情调的赌场里挥金如土——一掷千金的男人很能吸引寻欢中的女性。常与女性周旋的邦德更擅长于此。
But with the US close to full employment and inflation moving up towards the target, “you can see how tighter policy would be warranted,” he says. “It wouldn’t take a whole lot to shift the equation.”
明星大撞衫 看谁更好看(二)

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 佛山照明换帅 钟信才交棒空降兵
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 国内钛白粉价格持续下跌
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Maddie is so well recognised these days that a trip to Topshop results in her being mobbed by screaming tween fans who all want a selfie with their idol - something that has been tough to adjust to.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

反对:在颁奖季前一年早早上映可能不利于其冲奖。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Law
在根据真实罪案改编的电影《狐狸猎手》(Foxcatcher)中,以出演喜剧闻名的演员史蒂夫·卡瑞尔(Steve Carell)饰演大富翁约翰·E·杜邦(John E. du Pont)时隐藏在假面具后面。这个造型最突出的就是鸟嘴状鼻子。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

这次奠基之战借鉴了查克·温柏和拳王阿里的比赛,这个无名小卒温柏成了在阿里的职业生涯中击倒过他的区区4人之一。和电影里一样,温柏与阿里打了15回合,尽管他看起来(感觉也)像被卡车撞过。虽然他和洛奇最后都被对手技术性击倒,但温柏胜在启发了史泰龙塑造这个了不起的角色。
然而,至少有两名哈佛教授对取消入学资格的做法表示质疑。哈佛大学法学院荣誉教授艾伦?德肖维茨告诉《卫报》,学生们因互相之间“开非常恶劣的玩笑”而失去哈佛的入学资格,这样的“惩罚太苛刻”。
新年就要到了,让我们给那些久未联系的朋友送封英文新年祝福邮件,表达一份深深的祝福吧!
['sep?reit]

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

换总部:随着丰田迁至德州,奔驰从新泽西搬往北卡罗来纳州或乔治亚州,斯巴鲁也要建它的新总部了。它的一个选择是搬到离其客户群更近的佛蒙特州。
n. 增加,附加物,加法

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

4. Mark Turner Quartet “Lathe of Heaven” (ECM) On his first proper album as a leader in 13 years, the tenor saxophonist Mark Turner favors slithery interplay with the trumpeter Avishai Cohen, and finds new purpose in post-bop protocols. There’s dry intrigue in his compositions, and supple exactitude in his rhythm team: Joe Martin on bass, Marcus Gilmore on drums.
根据中国海关总署(General Administration of Customs)发布的数据,12月份以美元计的出口额同比减少6.1%至2094.2亿美元。这一跌幅比经济学家预期的中数多了2.1个百分点,也大于11月份修正后1.6%的跌幅(修正前该数字为增长0.1%)。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

“If they, say, delay a customary process for Korean imports and take other retaliatory measures on Korean products, there is nothing Korea can do about it,” he said.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 人民日报:中国经济发展韧性十足
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

The website claims that "the more you sip, the smarter you (and the bottle) get," but in reality the more you sip, the drunker you get and the less information you'll retain.
土耳其副总理库尔图尔姆斯说,土耳其当局与伊拉克方面保持着接触。
A series of explosions on Aug. 12 that originated in a warehouse illegally storing hazardous chemicals in the port city of Tianjin killed 173 people, injured hundreds and left behind post-apocalyptic scenes of destruction. The blasts raised serious questions about the lax enforcement of safety regulations during China's rapid industrialization.
坦率地讲,这种行为意味着你还只是一个小女孩,还算不上女人。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

smart
There are few chief executive decisions that drew more attention this year than Yahoo(YHOO, Fortune 500) CEO Marissa Mayer's work-from-home ban. The policy was initially seen as highly controversial and had a lot of people upset because of its perceived lack of flexibility.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

The fear was over downward mobility and cultural changes; the anger was against immigrants and indifferent elites.
Most observers would think the single-aisle Comac C919’s first flight last May (pictured) is illustrative of this, but while it is a key milestone, it does not represent the whole story about what is happening in the industry. Two other events are much more telling.
The GM turnaround will drag on. Forget a 2010 IPO.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

He's lately begun taking meetings with the likes of Marissa Mayer and Rupert Murdoch. (Murdoch is chairman of News Corp, which owns The Wall Street Journal.) Though D'Aloisio's net worth at this point is merely eye-popping, not obscene, in his own youthful way he seems every bit as formidable as relative gray-hairs like 27-year-old Tumblr founder David Karp or 29-year-old Facebook wunderkind Mark Zuckerberg. 'He captivates a room,' says Joshua Kushner, founder of Thrive Capital, an early backer of Summly. 'He is incredibly self-aware for his age.'
周二,萨尔州成为德国第一个禁止外国政客拉票的地区。德国数个地方议会基于消防安全等技术原因,取消了土耳其部长们原计划的拉票集会。
知名安全机构SplashData近日发布2017年最糟糕密码榜单,统计于今年遭泄露的超过500万个密码。“123456”和“password”(密码)再度居首。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

故事背景设定于《星球大战3:西斯的复仇》和《星球大战4:新希望》之间,起义军盗取死星设计图,将很有可能成为被重金追杀的对象。对于电影详细情节,我们也不是很清楚。
周三,北京市发改委主任卢彦在新闻发布会上说:“我们将会在通州开展297个项目,例如建设地铁线和高速路及改善生态环境。”

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 建材行业如何化解品牌难题
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

达洛伊西奥也尽力维持着生活原本的样子。他的女友还是之前的那个女友。而且尽管他不再去学校了──坐在教室里就没空监管Summly的研发──他还是照常去找老师拿作业。他十分庆幸他的朋友不了解他企业家的那一面。而当我采访他的时候,他正准备和一群高中死党去希腊玩上一周。
日食
《极盗车神》特别有趣,虽然它未必会使你一直捧腹大笑,但全片都很欢乐。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Aoki-san is a pleasure to work withon storyboard. With Aoki-san on the team it feels like a sure thing. The visionof these animations will be perfect.
“加之相比创业,高校更注重培养学生的创新意识。这也是大学生创业意向如此低的另一个原因。”

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

The invulnerable singer broadened into a wider emotional palette – musical too, with guitars and brass lacing through synthetic beats and dub effects. It could recall art-rock godmother Kate Bush (see the single "Green Light").
TV Movie: “Sherlock: The Abominable Bride (Masterpiece)” (PBS)
Property prices in Hong Kong have surged over the past decade, but hit a peak in September when jitters about China’s economy took hold.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

不像那些狂热追星的小女孩,玛蒂认为她一直都能保持着冷静的头脑,即使在格莱美颁奖典礼这种场合。因为她将自己视为一个明星,所以她需要表现得体。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

conduct
Industrial production rose 6.1 per cent year on year in October, according to China’s National Bureau of Statistics, unchanged from September’s level and just below a median forecast from economists of 6.2 per cent.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Maddie is so well recognised these days that a trip to Topshop results in her being mobbed by screaming tween fans who all want a selfie with their idol - something that has been tough to adjust to.
Take multiple measures to cut costs.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

根据《中国社会保险发展年度报告2015》显示,全国城镇职工与城乡居民养老保险累计结余近4万亿元。
15. WeTransfer

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

He argues, however, that “US monetary policy is often just as important as domestic factors in explaining the incidence of EM crises, if not more important.”
全球很多国家的消费者都倾向于购买国产货,这帮助推升了本土品牌的品牌价值。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

supervision

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Believe it or not, this prize went to the US Government General Accountability Office (GAO) for issuing a report that recommended a report about another report of reports recommending reports... or something like that.
Lucy Kay 成为亚军,而正太组合 Bars and Melody 位列第三。
But in year-on-year terms Xiamen prices grew at the second-fastest rate of 43.9 per cent, outdone only by Hefei, capital of Anhui province, which grew 47.6 per cent. Annualised prices once again rose in 65 cities and fell in five, suggesting that while the cost of housing may not be escalating as quickly as before, it remains widespread and relatively resilient.
The demagogue’s campaign leads naturally to despotism — the tyranny of the majority that is a mask on the tyranny of one.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Glazer surely took something, again, from Kubrick, especially in the scene in which his alien is born in some dimensionless otherworld. He took something from Nic Roeg and The Man Who Fell to Earth and a little, perhaps, from David Lynch – of which, more in a moment. But alongside the sci-fi exoticism he brought the grit and sinew of contemporary realism, calling to mind the work of film-makers like Ken Loach, or even Abbas Kiarostami and the opening of his The Taste of Cherry, in which a desperately unhappy man drives around the itinerant labour markets of Teheran looking for someone to help him. These fantastic alien forms are scuffed with ordinariness and even bathos. The scene in which the alien uncomprehendingly watches Tommy Cooper on television is a masterpiece of tonal suspense.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

In early November the government further tightened controls over outbound investment by requiring regulatory approval for some foreign acquisitions conducted through an offshore entity.
但来自宾夕法尼亚州(Pennsylvania)的玛蒂?齐格勒(Maddie Ziegler),她的人生完全不是这么一回事。
This technology previously existed for arms, but legs are rather more complicated. And since a misread signal can send you jumping off a bridge or in front of a moving car, thought-controlled legs need more stringent programming than equivalent arms. As one of the researchers delicately put it, “If you're using a bionic arm and it misbehaves, the elbow may move slightly. If the prosthetic leg misbehaves . . . that could be quite a safety issue.”

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

RSPCA South Australia chief inspector Andrea Lewis said it was a "heartbreaking" case for staff.
勤勉尽责干事创业。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Pan Jiancheng, deputy head of the bureau's China Economic Monitoring and Analysis Center, said the increasing proportion of research and development expenditure to GDP indicates that the driving force of economic growth is transforming to innovation-focus from the traditional factors - exports and investment.
Finally, in the EMBA ranking, excluding joint programmes delivered with non-European schools, IMD of Switzerland, with an average salary of $261,397, is well ahead of Business School in second and IE Business School in third place.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

The Caixin-Markit manufacturing purchasing managers’ index dipped to 50.8 in November, down from 51 in October and coming closer to the 50-point threshold that delineates expansion from contraction. A median forecast from economists polled by Reuters had predicted a fall to 50.9.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

四线及以下城市居民在收入、教育、医疗、养老方面的经济压力与国家平均水平相近,而家庭和人际关系方面的压力比二三线城市大。
Arizona, Texas Head List Of Best States For Expected Job Growth
同行评审指由一个或多个与论文作者业务能力相当的人进行评估,这有助于对研究进行验证。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

在西方国家更新、更广泛的国民身份认同里,白人们也有自己的一席之地。但是除非他们接受这一点,“白”的危机仍会持续存在下去。
读:口齿-教练要求口齿伶俐。
A total of 3,077 new cases of HIV infection took place in colleges and universities across China in 2017, according to the National Health Commission (NHC) at a press conference on Friday.
As you graduate, my friends, remember what lies ahead of you is a world overflowing with beauty and potential; not just in the form of office corridors or Wall Street but a real, throbbing world, full of many mysteries and heady experiences. A number of us miss this simple truth.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

protection
中国财富榜每年的变化反映了中国资本的流动,显示了这个国家超级富豪的金融实力。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

该数据显示10月份下半月北京、天津、上海、深圳、厦门和郑州新建住宅价格出现了环比下滑。
n. 行星
“我跟她很像,我们真的就像一对老夫妇。”

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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The film version of the popular television series "Legend of Sword and Fairy", also known as Chinese Paladin starts shooting in Zhejiang Province today.
['traigl]

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